RX-105 | | Probechem Biochemicals

Chemical Structure : RX-105

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RX-105 (RX105)

货号: PC-20581Not For Human Use, Lab Use Only.

RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs).

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1 g		Get quote

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生物&药学活性

RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs).
RX-105 inhibited binding of L-selectin to heparin with IC50 of 15 uM, inhibited selectin, chemokine and cytokine binding to GAGs.
RX-105 (5-50 mg/kg) inhibited paw edema dose dependently in paw edema animal model.

物理化学性质&存储条件

分子量	582.80
分子式	C29H34N4O3S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(NC(S1)=C(C2=NC3=CC=CC=C3S2)C4=C1CN(CC)CC4)C5=CC=C(S(=O)(N(CCCC)CC)=O)C=C5

参考文献

1. Nicholas Harris, et al. Biochim Biophys Acta. 2014 Jan;1840(1):245-54.

RX-105 (RX105)

生物&药学活性

物理化学性质&存储条件

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RX-105 (RX105)

生物&药学活性

物理化学性质&存储条件

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