Pridopidine |CAS:346688-38-8 Probechem Biochemicals

Chemical Structure : Pridopidine

CAS No.: 346688-38-8

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Pridopidine (ACR16;FR-310826;ASP-2314;Huntexil)

货号: PC-63432Not For Human Use, Lab Use Only.

Pridopidine (ACR16, FR-310826, ASP-2314, Huntexil) is a selective and potent Sigma-1 receptor agonist.

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生物&药学活性

Pridopidine (ACR16, FR-310826, ASP-2314, Huntexil) is a selective and potent Sigma-1 receptor agonist.
Pridopidine also is a specific dopamine stabilizer without no partial agonism; shows robust dose-dependent striatal D2 occupancy with ED50 of 18.99 mg/kg s.c. in vivo, shows high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in rats.

物理化学性质&存储条件

分子量	281.414
分子式	C15H23NO2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(methylsulfonyl)phenyl)-1-propylpiperidin

参考文献

1. Natesan S, et al. J Pharmacol Exp Ther. 2006 Aug;318(2):810-8.

2. Nilsson M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jul;28(4):677-85.

3. Seeman P, et al. Synapse. 2009 Oct;63(10):930-4.

4. Pettersson F, et al. J Med Chem. 2010 Mar 25;53(6):2510-20.

Pridopidine (ACR16;FR-310826;ASP-2314;Huntexil)

生物&药学活性

物理化学性质&存储条件

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Pridopidine (ACR16;FR-310826;ASP-2314;Huntexil)

生物&药学活性

物理化学性质&存储条件

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