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首页-小分子抑制剂&激动剂-GPCR-Adrenergic Receptor-Photoazolol-2
Photoazolol-2

Chemical Structure : Photoazolol-2

CAS No.: 2481380-87-2

Photoazolol-2 (PZL-2)

货号: PC-28010Not For Human Use, Lab Use Only.

Photoazolol-2 is a photoswitchable β2-adrenergic receptor (β2AR) blocker (β-blocker) with IC50 of 106.6 nM (Cis-photoazolol-2), demonstrating higher antagonism upon illumination.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Photoazolol-2 is a photoswitchable β2-adrenergic receptor (β2AR) blocker (β-blocker) with IC50 of 106.6 nM (Cis-photoazolol-2), demonstrating higher antagonism upon illumination.

物理化学性质&存储条件

分子量 370.45
分子式 C20H26N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R,E)-N-(4-((3-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)diazenyl)phenyl)acetamide

参考文献

1. Anna Duran-Corbera, et al. J Med Chem. 2020 Aug 13;63(15):8458-8470.

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