Photoazolol-1 (PZL-1)

Chemical Structure : Photoazolol-1

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货号: PC-28009Not For Human Use, Lab Use Only.

Photoazolol-1 is a photoswitchable β2-adrenergic receptor (β2AR) blocker (β-blocker) with pEC50 of 7.73 (Dark, trans-photoazolol-1), 52-fold selective over under light condition (cis-photoazolol-1, pEC50=6.01).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Photoazolol-1 is a photoswitchable β2-adrenergic receptor (β2AR) blocker (β-blocker) with pEC50 of 7.73 (Dark, trans-photoazolol-1), 52-fold selective over under light condition (cis-photoazolol-1, pEC50=6.01).

物理化学性质&存储条件

分子量	370.45
分子式	C20H26N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(4-((2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)diazenyl)phenyl)acetamide

参考文献

1. Stipp R, et al. Angew Chem Int Ed Engl. 2026 Apr 27;65(18):e17995.

2. Anna Duran-Corbera, et al. J Med Chem. 2020 Aug 13;63(15):8458-8470.