PevD1-NRP inhibitor A6

Chemical Structure : PevD1-NRP inhibitor A6

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货号: PC-27711Not For Human Use, Lab Use Only.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

PevD1-NRP inhibitor A6 is a specific small molecule inhibitor of Verticillium dahliae effector protein PevD1-NRP interaction, specifically binds to PevD1 (SPR KD=35.3 uM), effectively blocks the PevD1-NRP complex formation.
A6 forms stable hydrogen bonds with the key residue E108, effectively inhibiting the interaction of the PevD1-NRP.
A6 exerts anti-verticillium wilt effects caused by Verticillium dahliae infection in plants.
Fungal effector protein PevD1 promotes disease progression by interacting with the host asparagine-rich protein (NRP) and disrupting cryptochrome 2 (CRY2)-mediated signaling.

物理化学性质&存储条件

分子量	400.49
分子式	C21H24N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-((5-(4-(1-hydroxyethyl)phenyl)furan-2-yl)(methyl)amino)ethyl)benzenesulfonamide

参考文献

1. Yang X, et al. J Biol Chem. 2026 Aug 10:113431.