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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-Parabulin
Parabulin

Chemical Structure : Parabulin

CAS No.: 2766184-58-9

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Parabulin

货号: PC-38234Not For Human Use, Lab Use Only.

Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.
    Parabulin specifically inhibits growth of protozoan parasites (EC50=6.5 uM, apicomplexan parasite Toxoplasma gondii) and inhibits their microtubule formation in vitro.

    物理化学性质&存储条件

    分子量 387.432
    分子式 C21H25NO6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-3-(3,4-dimethoxyphenyl)-N-(3,4,5-trimethoxybenzyl)acrylamide

    参考文献

    1. Natacha Gaillard, et al. EMBO Mol Med. 2021 Nov 8;13(11):e13818.

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