PSI-421 |CAS:1067186-56-4 Probechem Biochemicals

Chemical Structure : PSI-421

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PSI-421 (PSI 421;PSI421)

货号: PC-61287Not For Human Use, Lab Use Only.

PSI-421 is a potent, orally bioavailable P-selectin inhibitor with biacore IC50 of 56 uM, shows improved pharmacokinetic properties and oral efficacy in models of vascular injury compare with PSI-697.

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PSI-421 is a potent, orally bioavailable P-selectin inhibitor with biacore IC50 of 56 uM, shows improved pharmacokinetic properties and oral efficacy in models of vascular injury compare with PSI-697.

物理化学性质&存储条件

分子量	407.773
分子式	C20H13ClF3NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[1-(4-chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic acid

参考文献

1. Huang A, et al. J Med Chem. 2010 Aug 26;53(16):6003-17.

PSI-421 (PSI 421;PSI421)

生物&药学活性

物理化学性质&存储条件

参考文献

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PSI-421 (PSI 421;PSI421)

生物&药学活性

物理化学性质&存储条件

参考文献

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