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首页-小分子抑制剂&激动剂-GPCR-CGRP Receptor-PRT-064040
PRT-064040

Chemical Structure : PRT-064040

CAS No.:

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PRT-064040 (PRT064040)

货号: PC-27352Not For Human Use, Lab Use Only.

PRT-064040 is a potent, selective calcitonin gene-related peptide receptor (CGRP) antagonist with binding Ki of 26.67 pM (human CGRP receptor), effectively inhibits human αCGRP-induced cAMP production with IC50 of 22.29 pM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PRT-064040 is a potent, selective calcitonin gene-related peptide receptor (CGRP) antagonist with binding Ki of 26.67 pM (human CGRP receptor), effectively inhibits human αCGRP-induced cAMP production with IC50 of 22.29 pM.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Shuwen Du, et al. J Pharmacol Exp Ther. 2026 Jun 17;393(8):104966.

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