PF 1022A |CAS:133413-70-4 Probechem Biochemicals

Chemical Structure : PF 1022A

CAS No.: 133413-70-4

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PF 1022A (PF1022A;PF-1022A)

货号: PC-43003Not For Human Use, Lab Use Only.

PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes.

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5 mg	￥3800	In stock
25 mg	￥9800	In stock
100 mg	￥18800	In stock
250 mg		Get quote

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生物&药学活性

PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes; binds to GABA receptors, which might contribute to the anthelmintic effect, like other cyclodepsipeptides, PF1022A acts as an ionophore.

物理化学性质&存储条件

分子量	949.1794
分子式	C52H76N4O12
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 43 mg/mL
Chemical Name/SMILES	Cyclo[(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]

参考文献

1. Sasaki T, et al. J Antibiot (Tokyo). 1992 May;45(5):692-7.

2. Dornetshuber R, et al. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44.

3. Chen W, et al. Parasitol Res. 1996;82(2):97-101.

4. von Samson-Himmelstjerna G, et al. Parasitol Res. 2000 Mar;86(3):194-9.

PF 1022A (PF1022A;PF-1022A)

生物&药学活性

物理化学性质&存储条件

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PF 1022A (PF1022A;PF-1022A)

生物&药学活性

物理化学性质&存储条件

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