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首页-小分子抑制剂&激动剂-GPCR-mAChR-PF-3635659
PF-3635659

Chemical Structure : PF-3635659

CAS No.: 931409-24-4

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PF-3635659 (PF-03635659)

货号: PC-61894Not For Human Use, Lab Use Only.

PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).

    物理化学性质&存储条件

    分子量 444.58
    分子式 C28H32N2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(3-hydroxyphenoxy)-delta,delta-dimethyl-alpha,alpha-diphenyl-1-azetidinepentanamide

    参考文献

    1. Glossop PA, et al. J Med Chem. 2011 Oct 13;54(19):6888-904.

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