PAC1, ERα PROTAC |CAS:2158322-33-7 Probechem Biochemicals

Chemical Structure : PAC1

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PAC1 (Compound PAC1)

货号: PC-35040Not For Human Use, Lab Use Only.

PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation..

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生物&药学活性

PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation.

物理化学性质&存储条件

分子量	1674.93
分子式	C94H107N13O16
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((2S,3S)-8-Cyano-5-((2-methoxynaphthalen-1-yl)methyl)-2-methyl-3-((S)-2-(methylamino)propanamido)-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-1-carbonyl)-N-(2-(2-(2-((2-(4-((Z)-1-(4-((4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexan

参考文献

1. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1.

PAC1 (Compound PAC1)

生物&药学活性

物理化学性质&存储条件

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PAC1 (Compound PAC1)

生物&药学活性

物理化学性质&存储条件

参考文献

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