Oxathiapiprolin (DPX-QGU42)

Chemical Structure : Oxathiapiprolin

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货号: PC-28092Not For Human Use, Lab Use Only.

Oxathiapiprolin is a piperidinyl thiazole isoxazoline fungicide that targets oxysterol binding protein (OSBP), shows exceptional activity against plant diseases caused by oomycete pathogens.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Oxathiapiprolin is a piperidinyl thiazole isoxazoline fungicide that targets oxysterol binding protein (OSBP), shows exceptional activity against plant diseases caused by oomycete pathogens.
Oxathiapiprolin binds in the oxysterol-binding protein domain of Oomycetes.
Oxathiapiprolin shows remarkable activity against Pseudoperonospora cubensis in cucurbits.
Oxathiapiprolin affects all stages in the asexual life cycle of the pathogen, inhibits zoospore release, cystospore germination, lesion formation, lesion expansion, sporangiophore development and sporangial production.
Oxathiapiprolin suppresses sporulation of P. cubensis in naturally-infected leaves, exhibits trans-laminar activity, translocated acropetaly from older to younger leaves, and moved from the root system to the foliage.

物理化学性质&存储条件

分子量	539.53
分子式	C24H22F5N5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanone, 1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-

参考文献

1. Pasteris RJ, et al. Bioorg Med Chem. 2016 Feb 1;24(3):354-61.

2. Cohen Y. PLoS One. 2015 Oct 9;10(10):e0140015.