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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-ONO-0300302
ONO-0300302

Chemical Structure : ONO-0300302

CAS No.: 856689-51-5

ONO-0300302 (ONO0300302;ONO 0300302)

货号: PC-60145Not For Human Use, Lab Use Only.

ONO-0300302 (ONO0300302) is a novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ONO-0300302 (ONO0300302) is a novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM.
    ONO-0300302 shows excellent in vivo efficacy, represents a best research tool available to LPA-related diseases.

    物理化学性质&存储条件

    分子量 477.601
    分子式 C29H35NO5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-(1-((2S,3S)-2-((2,3-dihydro-1H-inden-2-yl)methyl)-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl)-1H-pyrrol-3-yl)propanoic acid

    参考文献

    1. Masahiko Terakado, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1281-1286.

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