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首页-小分子抑制剂&激动剂-GPCR-CRF Receptor-NVS-CRF38
NVS-CRF38

Chemical Structure : NVS-CRF38

CAS No.: 1207258-55-6

NVS-CRF38 (NVS-CRF 38;NVS-CRF-38)

货号: PC-42988Not For Human Use, Lab Use Only.

NVS-CRF38 is a potent, selective, orally bioavailable corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50 of 70 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NVS-CRF38 is a potent, selective, orally bioavailable corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50 of 70 nM.

    物理化学性质&存储条件

    分子量 351.4023
    分子式 C19H21N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Pyrazolo[5,1-b]oxazole, 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethyl-

    参考文献

    1. Stringer RA, et al. Xenobiotica. 2014 Oct;44(10):902-12.

    2. Stringer RA, et al. Drug Metab Dispos. 2014 May;42(5):954-62.

    3. Stringer RA, et al. Drug Metab Dispos. 2014 Jul;42(7):1117-24.

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