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首页-抗体药物偶连体和PROTACs-PROTAC-NP1192
NP1192

Chemical Structure : NP1192

CAS No.: 2966791-41-1

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NP1192 (NP-1192)

货号: PC-25951Not For Human Use, Lab Use Only.

NP1192 is a highly effective PROTAC degrader targeting NAT10, promotes NAT10 KD and inhibits ac4C modification, facilitates NAT10 degradation through the ubiquitin-proteasome system (UPS).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NP1192 is a highly effective PROTAC degrader targeting NAT10, promotes NAT10 KD and inhibits ac4C modification, facilitates NAT10 degradation through the ubiquitin-proteasome system (UPS).

    物理化学性质&存储条件

    分子量 734.88
    分子式 C39H42N8O5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Benzonitrile, 4-[2-[2-cyclopentylidene-1-[7-[4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]-7-oxoheptyl]hydrazinyl]-4-thiazolyl]-

    参考文献

    1. Ao K, et al. ACS Cent Sci. 2025 Sep 16;11(11):2087-2107.

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