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NEU-1953

Chemical Structure : NEU-1953

CAS No.: 2218480-85-2

NEU-1953 (NEU1953)

货号: PC-35984Not For Human Use, Lab Use Only.

NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NEU-1953 (NEU1953) is a potent inhibitor of P. falciparum with EC50 of 0.43 uM (T. brucei), demonstrates improved ADME profile over the NEU-961.

    物理化学性质&存储条件

    分子量 398.474
    分子式 C22H22N8
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-(2-(4-methylpiperazin-1-yl)pyrimidin-5-yl)-N-(pyrazin-2-yl)quinolin-4-amine

    参考文献

    1. Mehta N, et al. ACS Infect Dis. 2018 Apr 13;4(4):577-591.

    2. Bachovchin KA, et al. J Med Chem. 2018 Dec 19. doi: 10.1021/acs.jmedchem.8b01365.

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