Chemical Structure : NE-100 hydrochloride
CAS No.: 149409-57-4
货号: PC-60289Not For Human Use, Lab Use Only.
NE-100 hydrochloride is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1480 | In stock | |
10 mg | ¥2280 | In stock | |
25 mg | ¥3680 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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NE-100 hydrochloride is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM.
NE-100 dispalys 205-fold selectivity over sigma-2, 1,000-fold selectivity over D1, D2, PCP, α1, 5-HT1A and 5-HT2 receptors.
NE-100 shows antipsychotic activity in vivo.
分子量 | 391.97 | |
分子式 | C23H33NO2.HCl | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride |
1. Nakazato A, et al. J Med Chem. 1999 Mar 25;42(6):1076-87.
2. Berardi F, et al. Bioorg Med Chem. 2001 May;9(5):1325-35.
3. Ogawa S, et al. Eur J Pharmacol. 1994 Sep 22;263(1-2):9-15.
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