NDT-30805 | NLRP3 inhibitor | Probechem Biochemicals

Chemical Structure : NDT-30805

加入收藏

货号: PC-49268Not For Human Use, Lab Use Only.

NDT-30805 is a potent and selective small molecule NLRP3 inflammasome inhibitor with IC50 of 13 nM for IL-1β inhibition in PBMCs.

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

NDT-30805 is a potent and selective small molecule NLRP3 inflammasome inhibitor with IC50 of 13 nM for IL-1β inhibition in PBMCs.

分子量	414.531
分子式	C23H22N6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione

1. David Harrison, et al. ACS Med Chem Lett. 2022 Aug 1;13(8):1321-1328.