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首页-小分子抑制剂&激动剂-GPCR-CRF Receptor-NBI-27914
NBI-27914

Chemical Structure : NBI-27914

CAS No.: 184241-44-9

NBI-27914 (NBI 27914 )

货号: PC-21398Not For Human Use, Lab Use Only.

NBI-27914 is a potent, selective antagonist of corticotropin-releasing factor 1 (CRF1) receptor with Ki of 1.7 nM, shows no activity at CRF2 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NBI-27914 is a potent, selective antagonist of corticotropin-releasing factor 1 (CRF1) receptor with Ki of 1.7 nM, shows no activity at CRF2 receptors.

物理化学性质&存储条件

分子量 434.19
分子式 C18H20Cl4N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine

参考文献

1. T Z Baram, et al. Brain Res. 1997 Oct 3;770(1-2):89-95.

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