Chemical Structure : N205
货号: PC-35114Not For Human Use, Lab Use Only.
N205 is a novel anti-malaria compound with in vitro IC50 of 1.3 nM against Plasmodium falciparum (3D7).
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N205 is a novel anti-malaria compound with in vitro IC50 of 1.3 nM against Plasmodium falciparum (3D7); demonstrates excellent rodent pharmacokinetic and in vivo antimalarial efficacy studies in the mouse Plasmodium berghei and Plasmodium falciparum Pf3D70087/N9 severe combined immunodeficiency (SCID) mouse models.
分子量 | 455.595 | |
分子式 | C27H37NO5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. O' Neill PM, et al. Bioorg Med Chem. 2018 May 17. pii: S0968-0896(18)30203-7.
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