Milveterol hydrochloride |CAS:804518-03-4 Probechem Biochemicals

Chemical Structure : Milveterol hydrochloride

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Milveterol hydrochloride (GSK 159797 hydrochloride )

货号: PC-62005Not For Human Use, Lab Use Only.

Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold).

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生物&药学活性

Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold); demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.

Asthma

Phase 2 Discontinued

物理化学性质&存储条件

分子量	471.982
分子式	C25H30ClN3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-hydroxy-5-((R)-1-hydroxy-2-((4-(((R)-2-hydroxy-2-phenylethyl)amino)phenethyl)amino)ethyl)phenyl)formamide hydrochloride

参考文献

1. Jacobsen JR, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8.

2. Fuso L, et al. Curr Med Chem. 2013;20(12):1477-95.

3. Jacobsen JR, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30.

Milveterol hydrochloride (GSK 159797 hydrochloride )

生物&药学活性

物理化学性质&存储条件

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Milveterol hydrochloride (GSK 159797 hydrochloride )

生物&药学活性

物理化学性质&存储条件

参考文献

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