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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-Miconazole
Miconazole

Chemical Structure : Miconazole

CAS No.: 22916-47-8

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Miconazole (R18134)

货号: PC-27947Not For Human Use, Lab Use Only.

Miconazole (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Miconazole (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types.

物理化学性质&存储条件

分子量 416.12
分子式 C18H14Cl4N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

参考文献

1. Peeters F, et al. Arzneimittelforschung. 1973 Aug;23(8):1107-11.

2. Ghali ENHK, et al. ACS Omega. 2026 Jul 17;11(31):45913-45930.

3. Fang L, et al. Biochem Pharmacol. 2025 Nov;241:117126.

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