MS8588 | cGAS DUBTAC | Probechem Biochemicals

Chemical Structure : MS8588

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MS8588 (MS 8588)

货号: PC-22955Not For Human Use, Lab Use Only.

MS8588 is a first-in-class DUBTAC of cGAS, a key component of the cGAS-STING pathway, stabilizes cGAS and increases the cGAS downstream effector protein STING.

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生物&药学活性

MS8588 is a first-in-class DUBTAC of cGAS, a key component of the cGAS-STING pathway, stabilizes cGAS and increases the cGAS downstream effector protein STING.

物理化学性质&存储条件

分子量	912.97
分子式	C44H59Cl2N9O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N1-(2-(3-(6,7-dichloro-2-(2-hydroxyacetyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indol-9-yl)-1H-pyrazol-1-yl)ethyl)-N10-(2-(5-(4-(4-(dimethylamino)but-2-enoyl)-2-oxopiperazin-1-yl)thiophen-2-yl)ethyl)decanediamide

参考文献

1. Jin J, et al. Angew Chem Int Ed Engl. 2024 Aug 16:e202415168.

MS8588 (MS 8588)

生物&药学活性

物理化学性质&存储条件

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MS8588 (MS 8588)

生物&药学活性

物理化学性质&存储条件

参考文献

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