MRT-5702D

Chemical Structure : MRT-5702D

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货号: PC-26773Not For Human Use, Lab Use Only.

MRT-5702D is a specific molecular glue degrader targeting cereblon (CRBN), forms a CRBN-MRT-5702D-G3BP2 ternary complex to activate the ubiquitin-proteasome system for G3BP2 degradation.

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生物&药学活性

MRT-5702D is a specific molecular glue degrader targeting cereblon (CRBN), forms a CRBN-MRT-5702D-G3BP2 ternary complex to activate the ubiquitin-proteasome system for G3BP2 degradation.

物理化学性质&存储条件

分子量	621.11
分子式	C30H29ClN6O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,3S)-2-((2-chlorobenzyl)sulfonyl)-N-((3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)imidazo[1,2-a]pyridin-7-yl)methyl)-1-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

参考文献

1. Annunziato S, et al. Nat Struct Mol Biol. 2026 Mar;33(3):479-487.

2. Annunziato S, et al. bioRxiv, 2025: 2025.04. 30.651496.

MRT-5702D

生物&药学活性

物理化学性质&存储条件

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MRT-5702D

生物&药学活性

物理化学性质&存储条件

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