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首页-小分子抑制剂&激动剂-GPCR-Bombesin Receptor-MP-4222
MP-4222

Chemical Structure : MP-4222

CAS No.:

MP-4222 (MP4222)

货号: PC-27295Not For Human Use, Lab Use Only.

MP-4222 is a potent small molecule gastrin-releasing peptide receptor (GRPR) antagonist with binding IC50 of 21.2 nM, has equal selectivity over the neuromedin B receptor (NMBR).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MP-4222 is a potent small molecule gastrin-releasing peptide receptor (GRPR) antagonist with binding IC50 of 21.2 nM, has equal selectivity over the neuromedin B receptor (NMBR).

物理化学性质&存储条件

分子量 593.65
分子式 C32H34F3N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-((1-(2,6-difluoro-4-methoxyphenyl)cyclohexyl)methyl)-2-(3-(2-fluoropyridin-4-yl)ureido)-3-(1H-indol-3-yl)-2-methylpropanamide

参考文献

1. Zhou M, et al. Med Chem Res. 2026 Jun;35(6):1119-1140.

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