MMV675968 | Antifungal agent | Probechem Biochemicals

Chemical Structure : MMV675968

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MMV675968 (MMV 675968)

货号: PC-73100Not For Human Use, Lab Use Only.

MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box.

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生物&药学活性

MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box.
MMV675968 has been shown to be efficient against the planktonic form of C. albicans.
MMV675968 showed an antiplasmodial activity against P. falciparum.
MMV675968inhibited the growth of all four A. baumannii test strains with IC50 of 0.6-2.7 uM, IC90 of 0.7-3.9 uM, and MIC of 1.6-10 uM.

物理化学性质&存储条件

分子量	359.814
分子式	C17H18ClN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-6-(((2,5-dimethoxyphenyl)amino)methyl)quinazoline-2,4-diamine

参考文献

1. Spalenka J, et al. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01640-17.

2. Songsungthong W, et al. Sci Rep. 2019 Oct 30;9(1):15625.

MMV675968 (MMV 675968)

生物&药学活性

物理化学性质&存储条件

参考文献

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MMV675968 (MMV 675968)

生物&药学活性

物理化学性质&存储条件

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