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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-MMV026468
MMV026468

Chemical Structure : MMV026468

CAS No.: 1329674-83-0

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MMV026468 (MMV 026468)

货号: PC-22744Not For Human Use, Lab Use Only.

MMV026468 is a highly potent, picomolar inhibitor of blood-stage Plasmodium falciparum, targets MEP isoprenoid precursor biosynthesis, inhibits first MEP enzyme DXS or steps prior to DXS such as regulation of the MEP pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MMV026468 is a highly potent, picomolar inhibitor of blood-stage Plasmodium falciparum, targets MEP isoprenoid precursor biosynthesis, inhibits first MEP enzyme DXS or steps prior to DXS such as regulation of the MEP pathway.

物理化学性质&存储条件

分子量 310.78
分子式 C18H15ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

[4-[5-(3-Chloroanilino)pyridin-3-yl]phenyl]methanol

参考文献

1. Stephanie Kabeche, et al. Antimicrob Agents Chemother. 2024 Jul 22:e0123823.

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