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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-MMV022224
MMV022224

Chemical Structure : MMV022224

CAS No.: 2581277-82-7

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MMV022224 (TCMDC-132409, MMV-022224, TCMDC132409)

货号: PC-27181Not For Human Use, Lab Use Only.

MMV022224 (TCMDC-132409) is a potent inhibitor of P. falciparum in vitro with low resistance, targets P. falciparum protein kinase 6 (PfPK6) with IC50 of 0.8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MMV022224 (TCMDC-132409) is a potent inhibitor of P. falciparum in vitro with low resistance, targets P. falciparum protein kinase 6 (PfPK6) with IC50 of 0.8 uM.

物理化学性质&存储条件

分子量 384.53
分子式 C25H28N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,1'-((1H-pyrrolo[2,3-b]pyridine-2,4-diyl)bis(4,1-phenylene))bis(N,N-dimethylmethanamine)

参考文献

1. Aisha J Syed, et al. ACS Infect Dis. 2026 Jun 25. doi: 10.1021/acsinfecdis.6c00276.

2. Sibasish Sarangi, et al. Exp Parasitol. 2025 Jun:273:108947.

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