MMV020291 (MMV291)

Chemical Structure : MMV020291

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货号: PC-27971Not For Human Use, Lab Use Only.

MMV020291 (MMV291) is a specific antimalarial inhibitor of red blood cells (RBC) invasion, specifically blocks merozoite entry into RBCs, reduces actin polymerisation that is required by the merozoite stage parasites to invade RBCs.

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生物&药学活性

MMV020291 (MMV291) is a specific antimalarial inhibitor of red blood cells (RBC) invasion, specifically blocks merozoite entry into RBCs, reduces actin polymerisation that is required by the merozoite stage parasites to invade RBCs.

物理化学性质&存储条件

分子量	407.57
分子式	C21H33N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-((4-(tert-butyl)phenyl)sulfonyl)piperazin-1-yl)-1-(pyrrolidin-1-yl)propan-1-one

参考文献

1. Dans MG, et al. Int J Parasitol. 2020 Mar;50(3):235-252.