欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Vasopressin Receptor-ML389
ML389

Chemical Structure : ML389

CAS No.: 1622294-25-0

加入收藏

ML389 (ML 389)

货号: PC-62116Not For Human Use, Lab Use Only.

ML389 is a highly potent, selective vasopressin receptor 1a (V1a-R) antagonist with IC50 of 40 nM.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML389 is a highly potent, selective vasopressin receptor 1a (V1a-R) antagonist with IC50 of 40 nM.
    ML389 dispalys >1,250-fold selectivity over V1b-R, V2-R, and OXTR.
    ML389 has good brain penetration, no significant activity at four human cytochrome P450 subtypes, high binding for human and rodent plasma protein, and an encouraging in vivo pharmacokinetic profile in mice.

    物理化学性质&存储条件

    分子量 404.33
    分子式 C21H23Cl2N3O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(4-chlorophenyl)-1-(5-chloropyridin-2-yl)-N-(cyclopropylmethyl)piperidine-4-carboxamide

    参考文献

    1. Mittapalli G, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: