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首页-小分子抑制剂&激动剂-GPCR-Histamine Receptor-MK-7288
MK-7288

Chemical Structure : MK-7288

CAS No.: 936626-07-2

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MK-7288 (MK7288, MK 7288)

货号: PC-61337Not For Human Use, Lab Use Only.

MK-7288 is a selective histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MK-7288 is a selective histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome.
    MK-7288 significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials.

    物理化学性质&存储条件

    分子量 401.507
    分子式 C22H31N3O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-(2-(piperidin-1-yl)ethyl)-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide

    参考文献

    1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302.

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