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首页-抗体药物偶连体和PROTACs-PROTAC-M9101
M9101

Chemical Structure : M9101

CAS No.:

M9101

货号: PC-26926Not For Human Use, Lab Use Only.

M9101 is a potent, selective and in vivo active Aurora A PROTAC degrader with DC50 value of 2.3 nM in MD-MBA-231 cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

M9101 is a potent, selective and in vivo active Aurora A PROTAC degrader with DC50 value of 2.3 nM in MD-MBA-231 cells.

物理化学性质&存储条件

分子量 784.29
分子式 C38H38ClN9O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((5-chloro-2-((4-(4-(6-(2,6-dioxopiperidin-3-yl)-5,7-dioxo-3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol-2(1H)-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide

参考文献

1. Yulin Mao, et al. J Med Chem. 2026 May 29. doi: 10.1021/acs.jmedchem.6c00183.

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