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首页-小分子抑制剂&激动剂-GPCR-Vasopressin Receptor-Lixivaptan
Lixivaptan

Chemical Structure : Lixivaptan

CAS No.: 168079-32-1

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Lixivaptan (VPA-985, WAY-VPA 985)

货号: PC-25955Not For Human Use, Lab Use Only.

Lixivaptan (VPA-985, WAY-VPA 985) is a potent, selective and orally active vasopressin receptor V2 (V2R) antagonist with IC50 of 1.2 and 2.3 nM for human and rat V2R, respectively.

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50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lixivaptan (VPA-985, WAY-VPA 985) is a potent, selective and orally active vasopressin receptor V2 (V2R) antagonist with IC50 of 1.2 and 2.3 nM for human and rat V2R, respectively.

物理化学性质&存储条件

分子量 473.93
分子式 C27H21ClFN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-Chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)phenyl)-5-fluoro-2-methylbenzamide

参考文献

1. Albright JD, et al. J Med Chem. 1998 Jul 2;41(14):2442-4.

2. Chan PS, et al. Adv Exp Med Biol. 1998;449:439-43.

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