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首页-小分子抑制剂&激动剂-GPCR-mAChR-LY2119620
LY2119620

Chemical Structure : LY2119620

CAS No.: 886047-22-9

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LY2119620 (LY-2119620)

货号: PC-60326Not For Human Use, Lab Use Only.

LY2119620 is a potent, specific,positive allosteric modulator of muscarinic M2 and M4 receptors.

规格 价格 库存 数量
5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY2119620 is a potent, specific,positive allosteric modulator of muscarinic M2 and M4 receptors.
LY2119620 displays inimal allosteric agonism for M1, M3, M5 receptors.
LY2119620 enhances the potency of three muscarinic acetylcholine receptor agonists, ACh, Oxo-M and Iperoxo.

物理化学性质&存储条件

分子量 437.94
分子式 C19H24ClN5O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy] thieno[2,3-b]pyridine-2-carboxamide

参考文献

1. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6.

2. Croy CH, et al. Mol Pharmacol. 2014 Jul;86(1):106-15.

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