LPM3480226 (LY-01013)

Chemical Structure : LPM3480226

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货号: PC-49662Not For Human Use, Lab Use Only.

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

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生物&药学活性

LPM3480226 (LY-01013) is a potent, selective IDO1/TDO dual inhibitor, inhibits the initial and rate-limiting enzymes in tryptophan metabolism, which play an essential role in mediating immunosuppression in tumor microenvironment.

物理化学性质&存储条件

分子量	419.23
分子式	C12H12BrFN6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-ureidoethyl)thio)-1,2,5-oxadiazole-3-carboximidamide

参考文献

1. Patent WO2018024208 A1.