LOXO-195 R racemate |CAS:1350884-56-8 Probechem Biochemicals

Chemical Structure : LOXO-195 R racemate

CAS No.: 1350884-56-8

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LOXO-195 R racemate (LOXO 195;LOXO195)

货号: PC-60903Not For Human Use, Lab Use Only.

The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively..

规格	价格	库存
5 mg	￥1680	In stock
25 mg	￥3280	In stock
50 mg	￥5280	In stock
100 mg	￥8580	In stock
1 g		Get quote

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生物&药学活性

The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.

物理化学性质&存储条件

分子量	380.427
分子式	C20H21FN6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	100 mM in DMSO (38 mg/mL)
Chemical Name/SMILES	(13E,14E,22S)-35-fluoro-6-methyl-7-aza-1(5,3)-pyrazolo[1,5-a]pyrimidina-3(3,2)-pyridina-2(1,2)-pyrrolidinacyclooctaphan-8-one

参考文献

1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972.

LOXO-195 R racemate (LOXO 195;LOXO195)

生物&药学活性

物理化学性质&存储条件

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LOXO-195 R racemate (LOXO 195;LOXO195)

生物&药学活性

物理化学性质&存储条件

参考文献

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