KLHDC2-AR PROTAC K2-AR-1

Chemical Structure : KLHDC2-AR PROTAC K2-AR-1

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货号: PC-22820Not For Human Use, Lab Use Only.

KLHDC2-AR PROTAC K2-AR-1 is a hihgly potent KLHDC2-directed PROTAC degrader of androgen receptor (AR), wihch is dependent on the UPS and KLHDC2.

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KLHDC2-AR PROTAC K2-AR-1 is a hihgly potent KLHDC2-directed PROTAC degrader of androgen receptor (AR), wihch is dependent on the UPS and KLHDC2.

分子量	1051.27
分子式	C60H71FN8O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl 2-(5-(7-(4-(4-((1-(4-(((1r,3r)-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-2-fluorobenzoyl)-3-isobutyl-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl)-2-oxopyridin-1(2H)-yl)acetate

1. Hickey CM, et al. Nat Struct Mol Biol. 2024 Feb;31(2):311-322.