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首页-小分子抑制剂&激动剂-GPCR-CRF Receptor-K41498
K41498

Chemical Structure : K41498

CAS No.: 434938-41-7

K41498 (K 41498)

货号: PC-21400Not For Human Use, Lab Use Only.

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

K41498 is a potent, highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.

物理化学性质&存储条件

分子量 3632.22
分子式 C162H276N48O46
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{D-Phe}-His-Leu-Leu-Arg-Lys-{Nle}-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2

参考文献

1. Erspamer V, et al. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):265-70.

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