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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-JPC-3210
JPC-3210

Chemical Structure : JPC-3210

CAS No.: 1609655-35-7

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JPC-3210 (JPC3210)

货号: PC-62611Not For Human Use, Lab Use Only.

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.
    JPC-3210 exhibits longer plasma elimination half-life, and excellent in vivo efficacy against murine malaria.

    物理化学性质&存储条件

    分子量 398.446
    分子式 C21H26F4N2O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(tert-butyl)-2-((tert-butylamino)methyl)-6-(5-fluoro-6-(trifluoromethyl)pyridin-3-yl)phenol

    参考文献

    1. Chavchich M, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8.

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