JNJ19567470 | CRF1 antagonist | Probechem Biochemicals

Chemical Structure : JNJ19567470

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JNJ19567470 (R317573, CRA5626, JNJ-19567470)

货号: PC-27084Not For Human Use, Lab Use Only.

JNJ19567470 (JNJ-19567470, R317573, CRA5626) is a potent, selective, non-peptide CRF receptor 1 (CRF1, CRFR1) antagonist, prevents sodium lactate-induced acute panic-like responses.

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生物&药学活性

JNJ19567470 (JNJ-19567470, R317573, CRA5626) is a potent, selective, non-peptide CRF receptor 1 (CRF1, CRFR1) antagonist, prevents sodium lactate-induced acute panic-like responses.

物理化学性质&存储条件

分子量	443.39
分子式	C22H27BrN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1-(7-(4-bromo-2,6-dimethylphenyl)-2,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl)methanol

参考文献

1. Anantha Shekhar, et al. Int J Neuropsychopharmacol. 2011 Apr;14(3):355-65.

2. Zhou J, et al. Regul Toxicol Pharmacol. 2025 Sep;161 Suppl 1:105334.

JNJ19567470 (R317573, CRA5626, JNJ-19567470)

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物理化学性质&存储条件

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JNJ19567470 (R317573, CRA5626, JNJ-19567470)

生物&药学活性

物理化学性质&存储条件

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