欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Histamine Receptor-JNJ-39758979
JNJ-39758979

Chemical Structure : JNJ-39758979

CAS No.: 1046447-90-8

加入收藏

JNJ-39758979 (JNJ 39758979, JNJ39758979)

货号: PC-60793Not For Human Use, Lab Use Only.

JNJ-39758979 is a potent, selective, orally bioavailable histamine H4 receptor antagonist with Ki of 12.5 nM, >80-fold selectivity over other histamine receptors.

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥4280 In stock
50 mg ￥7280 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

JNJ-39758979 is a potent, selective, orally bioavailable histamine H4 receptor antagonist with Ki of 12.5 nM, >80-fold selectivity over other histamine receptors.
JNJ-39758979 shows dose-dependent activity in models of asthma and dermatitis, has good pharmacokinetics.

物理化学性质&存储条件

分子量 221.308
分子式 C11H19N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-4-(3-amino-pyrrolidin-1-yl)-6-isopropyl-pyrimidin-2-ylamine

参考文献

1. Savall BM, et al. J Med Chem. 2014 Mar 27;57(6):2429-39.

2. Thurmond RL, et al. J Pharmacol Exp Ther. 2014 May;349(2):176-84.

3. Kollmeier A, et al. J Pharmacol Exp Ther. 2014 Jul;350(1):181-7.

4. Murata Y, et al. J Dermatol. 2015 Feb;42(2):129-39.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: