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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-JCP174
JCP174

Chemical Structure : JCP174

CAS No.: 126062-19-9

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JCP174 (JCP-174)

货号: PC-23296Not For Human Use, Lab Use Only.

JCP174 is a small molecule inhibitor of Toxoplasma gondii palmitoyl-protein thioesterase-1 (TgPPT1), enhances Toxoplasma host-cell invasion, triggers secretion of invasion-associated organelles, increases motility and enhances the invasive capacity of tachyzoites.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JCP174 is a small molecule inhibitor of Toxoplasma gondii palmitoyl-protein thioesterase-1 (TgPPT1), enhances Toxoplasma host-cell invasion, triggers secretion of invasion-associated organelles, increases motility and enhances the invasive capacity of tachyzoites.

物理化学性质&存储条件

分子量 253.68
分子式 C12H12ClNO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-Amino-4-chloro-3-propoxy-isochromen-1-one

参考文献

1. Child MA, et al. Nat Chem Biol. 2013 Oct;9(10):651-6.

2. Powers JC, et al. Biochemistry. 1990 Mar 27;29(12):3108-18.

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