JB300 | Aurora A PROTAC | Probechem Biochemicals

Chemical Structure : JB300

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货号: PC-24081Not For Human Use, Lab Use Only.

JB300 is a potent, highly selective PROTAC degrader of Aurora A with DC50 of 30 nM.

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JB300 is a potent, highly selective PROTAC degrader of Aurora A with DC50 of 30 nM.

分子量	906.38
分子式	C43H45ClFN7O10S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclohexanecarboxamide, 4-(3-chloro-2-fluorophenoxy)-N-[2-[2-[2-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]ethoxy]ethoxy]ethyl]-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-, trans-

1. Bozilovic, et al. Current Research in Chemical Biology 2 (2022): 100032.

2. Rishfi M, et al. Eur J Med Chem. 2023 Feb 5;247:115033.