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首页-小分子抑制剂&激动剂-GPCR-mAChR-Iperoxo
Iperoxo

Chemical Structure : Iperoxo

CAS No.: 247079-84-1

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Iperoxo (mAChR agonist Iperoxo)

货号: PC-60327Not For Human Use, Lab Use Only.

Iperoxo is an extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively.

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10 mg ￥1980 In stock
25 mg ￥2980 In stock
50 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Iperoxo is an extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively.
Iperoxo significantly exceeds ACh in Gi /Gs signalling competence CHO-hM2 cells.

物理化学性质&存储条件

分子量 324.16
分子式 C10H17IN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[(4,5-Dihydro-3-isoxazolyl)oxy]-N,N,N-trimethyl-2-butyn-1-aminium iodide

参考文献

1. Schrage R, et al. Br J Pharmacol. 2013 May;169(2):357-70.

2. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6.

3. Croy CH, et al. Mol Pharmacol. 2014 Jul;86(1):106-15.

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