Chemical Structure : INF39
CAS No.: 866028-26-4
货号: PC-35385Not For Human Use, Lab Use Only.
INF39 (NLRP3 inhibitor INF39) is a nontoxic, irreversible, orally available NLRP3 inhibitor that inhibits NLRP3 ATPase and decreases interleukin-1β release from macrophages.
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---|---|---|---|
5 mg | ¥1280 | In stock | |
10 mg | ¥1980 | In stock | |
25 mg | ¥2980 | In stock | |
50 mg | ¥4580 | In stock | |
100 mg | Get quote |
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INF39 (NLRP3 inhibitor INF39) is a nontoxic, irreversible, orally available NLRP3 inhibitor that inhibits NLRP3 ATPase and decreases interleukin-1β release from macrophages.
INF39 significantly inhibit ATP- and nigericin-induced IL-1β release in mouse bone marrow derived macrophages (BMDM) at 10 uM.
INF39 reduces colonic myeloperoxidase, IL-1β, and TNF Levels in DNBS-treated rats.
分子量 | 224.684 | |
分子式 | C12H13ClO2 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Ethyl 2-(2-chlorobenzyl)acrylate |
1. Cocco M, et al. J Med Chem. 2017 May 11;60(9):3656-3671.
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