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首页-抗体药物偶连体和PROTACs-PROTAC-Gridegalutamide
Gridegalutamide

Chemical Structure : Gridegalutamide

CAS No.: 2446929-86-6

Gridegalutamide (BMS-986409)

货号: PC-23836Not For Human Use, Lab Use Only.

Gridegalutamide (BMS-986409) is an orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Gridegalutamide (BMS-986409) is an orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity.

物理化学性质&存储条件

分子量 818.92
分子式 C41H45F3N8O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(2R)-4-[2-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-ethylphenoxy]ethyl]-2-methylpiperazin-1-yl]-N-[3-[[(3R)-2,6-dioxopiperidin-3-yl]amino]phenyl]acetamide

参考文献

1. Patent WO2020132014 A1.

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