GSK717 | NOD2 inhibitor | Probechem Biochemicals

Chemical Structure : GSK717

CAS No.: 1595278-21-9

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GSK717 (GSK-717)

货号: PC-38557Not For Human Use, Lab Use Only.

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.

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50 mg	￥4280	In stock
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生物&药学活性

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.

物理化学性质&存储条件

分子量	452.55
分子式	C28H28N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[2-(Benzoylmethylamino)ethyl]-N-(2,3-dihydro-1H-inden-5-yl)-1H-benzimidazole-1-acetamide

参考文献

1. Rickard DJ, et al. PLoS One. 2013 Aug 1;8(8):e69619.

GSK717 (GSK-717)

生物&药学活性

物理化学性质&存储条件

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GSK717 (GSK-717)

生物&药学活性

物理化学性质&存储条件

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