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GNF179

Chemical Structure : GNF179

CAS No.: 1261114-01-5

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GNF179 (KAF179)

货号: PC-47013Not For Human Use, Lab Use Only.

GNF179 is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.

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5 mg ￥2580 In stock
10 mg ￥3980 In stock
25 mg ￥6580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GNF179 (KAF179) is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.

物理化学性质&存储条件

分子量 427.908
分子式 C22H23ClFN5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethan-1-one

参考文献

1. Meister S, et al. Science. 2011 Dec 9;334(6061):1372-7.

2. Lim MY, et al. Nat Microbiol. 2016 Sep 19;1:16166.

3. Magistrado PA, et al. ACS Infect Dis. 2016 Nov 11;2(11):816-826.

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