Fosmanogepix (APX001) | Gwt1 inhibitor | Probechem Biochemicals

Chemical Structure : Fosmanogepix

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货号: PC-35452Not For Human Use, Lab Use Only.

Fosmanogepix (APX001, E1211) is a novel antifungal agent, the prodrug form of Manogepix, which inhibits the fungal protein Gwt1.

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Fosmanogepix (APX001, E1211) is a novel antifungal agent, the prodrug form of Manogepix, which inhibits the fungal protein Gwt1.

分子量	468.406
分子式	C22H21N4O6P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyridinium, 2-amino-1-[(phosphonooxy)methyl]-3-[3-[[4-[(2-pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-, inner salt

1. Hager CL, et al. Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e02319-17.
2. Dai X, et al. Nat Commun. 2024 Oct 24;15(1):9194.