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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-Fexinidazole
Fexinidazole

Chemical Structure : Fexinidazole

CAS No.: 59729-37-2

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Fexinidazole (HOE 239)

货号: PC-25297Not For Human Use, Lab Use Only.

Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.

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10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.

物理化学性质&存储条件

分子量 279.31
分子式 C12H13N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Methyl-2-((4-(methylthio)phenoxy)methyl)-5-nitro-1H-imidazole

参考文献

1. Kaiser M, et al. Antimicrob Agents Chemother. 2011 Dec;55(12):5602-8.

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